Vinegar

Vinegar made from wine

Numbers 6:1–4 See also Ruth 2:14

And the LORD said to Moses, “Speak to the Israelites and tell them that if a man or woman makes a special vow, the vow of a Nazirite, to separate himself to the LORD, he is to abstain from wine and strong drink. He must not drink vinegar made from wine or strong drink, and he must not drink any grape juice or eat fresh grapes or raisins. All the days of his separation, he is not to eat anything that comes from the grapevine, not even the seeds or skins.

Vinegar as an acid, reacting vigorously with alkaline soda

Proverbs 25:20

Like one who removes a garment on a cold day or vinegar poured on a wound is one who sings songs to a heavy heart.

Vinegar as a substitute for wine

Its unpleasantness

Proverbs 10:26 See also Psalm 69:19–22

Like vinegar to the teeth and smoke to the eyes, so is the slacker to those who send him.

It was offered to Jesus Christ at the crucifixion

Matthew 27:48–50 parallels Mark 15:36–37, Luke 23:36–37, John 19:28–30 See also Psalm 69:21

One of them quickly ran and brought a sponge. He filled it with sour wine, put it on a reed, and held it up for Jesus to drink. But the others said, “Leave Him alone. Let us see if Elijah comes to save Him.” When Jesus had cried out again in a loud voice, He yielded up His spirit.